Contrast Reactions & Premedication

PreMedication For Contrast Allergies

Adult Out-patients:

• 50 mg prednisone PO 13, 7 and 1 hour before the injection AND

• 50 mg diphenhydramine (Benadryl) IV/PO within 1 hour of the injection.

Adult ED and In-Patients:

• 200 mg hydrocortisone IV 4 hours before injection AND

• 50 mg diphenhydramine (Benadryl) IV/PO within 1 hour of the injection.

Additional premedication options

Additional Information on CT contrast including background information, contrast extravasation and patients on dialysis.